The acquity uplc system is to be used for in vitro diagnostic use only by trained, qualified laboratory personnel. The ltq xl with etd option won a silver award as one of the best new products seen by industry editors attending pittcon 2007. Refurbished thermo ltq xl iet refurbished analytical. The xl crystals are the most aggressive and ideal for most paint removal applications. Automated data dependent msn acquisition with accurate mass analysis can be effortlessly combined with rapid lcms analysis. Explore our getting started and troubleshooting sections for solutions to top inquiries and common problems. Ltq orbitrap velos hardware manual brown university. Simply cannot get the thermo ltq ion trap ms tune pass the manufactures suggestion. Convenient reporting software displays full scan and product ion mass spectra for each expected metabolite in order to verify predicted biotransformations. Thermo finnigan ltq orbitrap mass spectrometer system. Pulsed q collision induced dissociation pqd is a patented technique that eliminates the low mass cutoff concern inherent with all ion traps. Ltq xl ion max api source enhanced sensitivity and ruggedness sweep gas reduces chemical noise.
Product specifications the ltq xl extends the msn performance of the ltq linear ion trap with powerful new tools to generate extensive structural information for the most demanding proteomics and metabolism applications. Thermo ltq xl linear ion trap mass spectrometer extends the renowned performance of the ltq. Im in the dark, im use to a sciex 5600 and its totally different software, source etc than the ltq orbi xl etd and i am new using it with no one working with me to ask when i have questions. Thermo finnigan ltq orbitrap mass spectrometer system priced to sell.
Using multiple dissolution techniques, including pulsedq dissociation pqd and electron transfer dissociation etd, the ltq xl generates extensive structural information for the most demanding proteomics samples. Ion trap allows for msms analysis in a variety of applications including drug metabolism, food science, forensic lab toxicology and clinical settings. Within the pm task record, you can include a detailed description with task procedures, guidelines and any other important information. Troubleshooting ltq and ltqorbitrap lcmsms systems with massqc. Rp54troubleshooting liquid chromatography tandem mass spectrometry lcmsms systems is a top priority in academic and commercial proteomics laboratories. Formulated using our largest xl crystals and our standard moisture control system, moistureguard 2, absorbing moisture before can cause flow problems. Ltq xl linear ion trap mass spectrometer thermo scientific. If the item comes with a computer andor software, installed andor media. Net assembly for reading our raw, sld, and pmd files. For course dates, availability and any questions, please call 1.
Thermo scientific ltq orbitrap xl gentech scientific. Unparalleled sensitivity and unmatched ms n spectral quality. Maldi ltq xl operations onsite at your facility 4 days. The ltq orbitrap xl is a member of the family of ltq mass spectrometer ms hybrid instruments. No matter what we tries, the peah 524 marfa is only at 30% of the base peak supposed to be aound 60%. Who uses this guide this ltq orbitrap xl hardware manual is intended for all personnel. The ltq orbitrap xl etd is a member of the family of ltq mass spectrometer ms hybrid instruments. The ltq xl ion trap ms extends the legendary ms n performance of the ltq ion trap, incorporating more techniques to generate structural information through innovations in thermo scientific ion trap technology unparalleled sensitivity and unmatched ms n spectral quality. Unprecedented analytical power thermo fisher scientific. Pulsed q dissociation pqd for generating more fragments and extending the low mass range. Feature rich, easy to use cmms software ftmaintenance cmms. Does anyone have an outline for ltq orbi xl etd parameter. The new collision cell adds more flexibility to any msms experiment.
Linear ion trap mass spectrometer with etd electron transfer dissociation capabilities. The thermo ltq is a 2d linear ion trap ms, first released circa 2003. The addition of maldi to the ltq xl linear ion trap provides informationrich. Ltq series hardware manual thermo fisher scientific. When purchasing a preowned ion trap mass spec, look for experienced companies who offer refurbishment and warranties to support your purchase. Thermo finnigan ltq msms ion max esi source gentech. Variants include the ltq, ltq ft circa 2003, ltq orbitrap circa 2005, ltq xl electrontransfer dissociation, etd circa 2007, ltq orbitrap xl circa 2007, ltq discovery, ltq ft ultra, ltq velos circa 200910, ltq orbitrap velos circa 200910. This ltq xl getting started manual provides information on how to set up, calibrate, and tune.
The reagent intensity can be recovered with manual tuning, and the procedure for doing so. Reduced maintenance the very open design of the stacked ring electrodes in the slens facilitates efficient removal of solventladen gas. With unparalleled sensitivity and ultrafast cycle time, the ltq xl delivers more information from less sample in less time. Ftmaintenance cmms provides a full range of features for documenting, managing, and tracking maintenance activities from a simple, allinone platform. It combines three different and complementary fragmentation techniques cid, hcd, and etd with the proven benefits of orbitrap technology. Hello all, i am having the communication problem between the lc and the software. Orbitrap tribrid ms series instrument control software version 3. Ltq orbitrap xl mass spectrometer a superior alternative to qtof systems. Api ion source ltq xl linear ion trap ctrap hcd collision cell orbitrap mass analyzer. The orbitrap tribrid series hardware manual describes the modes of operation and hardware components for the thermo scientific orbitrap tribrid series mass spectrometer ms system.
Troubleshooting ltq and ltqorbitrap lcmsms systems with. Expected modifications view a custom list of expected modi. Welcome to the thermo scientific ltq orbitrap xl etd system. Note thermo fisher scientific no longer ships the ltq velos and lxq mass. Welcome to the thermo scientific, ltq orbitrap xl system. About this guide this ltq orbitrap xl hardware manual contains a description of the modes of operation and principle hardware components of your ltq orbitrap xl instrument. Thermo scientific ltq xl ion trap mass spectrometer with. Principle of operation schematic of the ltq orbitrap xl. Has anyone replaced the turbopump in an ltq xl mass spectrometer. Thermo scientific ltq xl getting started 176 pages brand. Thermo ltq xl linear ion trap mass spectrometer gentech. The thermo ltq xl delivers more structural information than any other ion trap mass spectrometer. Ltq orbitrap operations 4 days training unity lab services.
The tube lens voltage seems to be the major factore affecting the relative peak intensity for low caffeine at 195 and high mass ultarmark at 1222, 22. Hesi source, nano spray probe, nano source housing with pulnix camera pn 31012584, xcalibur 2. Ltq family with etd operations 2326 ltq orbitrap operations 912 2023 36 25 ltq orbitrap with etd operations 1821 212 ltq family biotech operations 1619 2427 ltq orbitrap biotech operations 2326 47 1417 1619 q exactive operations 25 2730 q exactive biotech. Maldi ltq xl operations onsite at your facility 4 days this course is an alternative to the electrospray ionization method esi, and will introduce experienced thermo scientific ltq xl operators to the matrixassisted laser desorption ionization thermo scientific maldi method for the structural analysis of peptides and the. Product specifications ltq xl more structural information. Preventive maintenance management software emaint cmms. The ltq xl ion trap ms extends the legendary ms n performance of the ltq ion trap, incorporating more techniques to generate structural information through innovations in thermo scientific ion trap technology. The addition of etd to the ltq xl linear ion trap mass spectrometer provides significant advantages for proteinpeptide characterization, posttranslational modification ptm analysis and topdown or middledown sequencing of proteins and peptides. The acquity uplc system is cemarked according to the european union in vitro diagnostic device directive 9879ec. Improved sensitivity through enhanced ion transmission using an. Refurbished thermo ltq xl high performance linear ion trap mass spectrometer complete with ion max api source, hesi probe pn opton20032, edwards roughing pumps and pc with new xcalibur 2.
Maintenance xl blasting media armex soda blasting media. Apci probe pn opton2012, nanospray probe, michrom bioresources captivespray ion source pn ss20000300. View online or download thermo scientific ltq xl getting started, getting started manual. About this guide this ltq orbitrap xl etd hardware manual contains a description of the modes of operation and principle hardware components of your ltq orbitrap xl etd instrument. Thermo scientific ltq orbitrap xl the most confident protein identification. The thermo scientific ltq orbitrap xl hybrid ftms fourier transform mass spectrometer supports a wide range of applications from routine compound identification to the most challenging analysis of low level components in complex mixtures. Ions generated by api are collected in the ltq xl followed by axial ejection to the cshaped storage trap which is used to store and collisionally. If you are paying with a credit card, our training registrar will contact you within two business days to confirm course dates. Powerful integrated software for characterization of biotherapeutics. If you are using a voucher to purchase this course, please call 18005324752 to speak with our training registrar.
The ltq xl extends the renowned ms performance of the ltq linear ion trap with powerful new tools to generate extensive structural information for the most demanding proteomics and metabolism applications. Access to our expert service team, information on support plans, parts and. We present a new software tool, massqc, that builds on work from the national institute of standards. Orbitrapbased and ltq ft ultra instruments and the known mass defects for different biotransformations. The thermo scientific ltq orbitrap xl etd is the most powerful instrument for proteomics analyses. The high mass accuracy of the ltq orbitrap velos increases the speed and con. All positive and negative calibrationchecks passed accept in the trap in negative mode, the ion electron mult gain. Improved sensitivity through enhanced ion transmission. Has anyone replaced the turbopump in an ltq xl mass. The ltq xl linear ion trap technology you can trust.
Equipped with an electrospray ionization esi source, the ltq boasts improved capacity and trapping efficiency, higher scan speed and increased sensitivity. The ltq ft ultra system is a fully integrated hydrid mass spectrometer consisting of a linear ion trap mass spectrometer, ltq xl, combined with a fourier transform ion cyclotron resonance mass spectrometer. It also provides the instruments cleaning and maintenance procedures. Preventive maintenance scheduling software emaint cmms maintenance software lets you define an unlimited number of calendar andor meterbased pm tasks for each asset. Warning symbols alert the user to check for hazardous conditions. Thermo ltq xl iontrap ms tuning help chromatography forum. We, at spec india, have proven experience in delivering 365x24x7 sla driven software maintenance and support services, which are quality and commitment focused, to a wide range of clientele executing a diverse range of software business solutions. Table 1 contrasts the ltq velos performance with that of the earlier ltq xl linear ion trap. Thermo finnigan ltq orbitrap ms eci source powervar series 2000 gpi global power interface 2 edwards roughing pumps with connectors thermo scientific neslab themoflex 9000 chiller computer system superior mass accuracy, mass resolution, high productivity, low. The ltq xl linear ion trap mass spectrometer delivers confident structural information in routine applications keywords exceptional sensitivity and flexibility for proteomics and metabolism applications.
General purpose surface preparation and coatings removal. Ltq xl linear ion trap mass spectrometer support troubleshooting velos pro dualpressure linear ion trap mass spectrometer support orbitrap elite hybrid ion traporbitrap mass spectrometer support. Ltq orbitrap xl hardware manual thermo fisher scientific. The ltq orbitrap xl features a rapid scan rate, high mass accuracy, and up to 100k resolution power. The ltq orbitrap xl etd system where the etd module is.
Ltq orbitrap xl offering outstanding mass accuracy, resolving power, dynamic range, and high sensitivity the hybrid ft mass spectrometer combines a linear ion trap ms and the orbitrap mass analyzer. Thermo scientific ltq orbitrap xl from thermo fisher. From small molecules to large, receive training on system calibration and maintenance, builtin workflows and advanced, custom method execution to allow you to increase your impact within the. Thermo scientific ltq orbitrap xl etd from thermo fisher. Ltq xl linear ion trap mass spectrometer support thermo.
Product specifications ltq xl more structural information with ms. Mar 31, 2005 simply cannot get the thermo ltq ion trap ms tune pass the manufactures suggestion. We have 2 thermo scientific ltq xl manuals available for free pdf download. Thank you for watching gentech scientific visit our site. Thermo scientific ltq xl ion trap ms with pc conquer scientific. Mar 04, 2015 superior mass accuracy, mass resolution, dynamic range, detection power, high productivity, and low maintenance.
Computerkeyboard, monitor, mouse, desktop with xcalibur software. In addition, this manual provides stepbystep instructions for cleaning and maintaining your instrument. Ltq xl is the only mass spectrometer that offers multiple dissociation techniques, pqd, etd and cid. Superior mass accuracy, mass resolution, dynamic range, detection power, high productivity, and low maintenance. This ltq orbitrap xl hardware manual contains a description of the modes of operation and principle hardware components of your ltq orbitrap xl instrument. Browse through our guides and tools section to access a comprehensive portfolio of productrelated support resources. Automatically generate work orders, track work order completion, and access work orders from anywhere with easytouse ftmaintenance cmms software. Excited by the power and potential of your thermo scientific orbitrapbased mass spectrometer. For course dates, availability and any questions, please call 18005324752 or.
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